So instead of this paper being treated as confirming an earlier hypothesis, it was treated as generating a novel hypothesis. The CDC has advised everyone to wear a mask. NIH is still unsure whether fluvoxamine should be used to treat COVID (article I did after the TOGETHER trial). Early treatment with existing drugs is the fastest, most effective, and lowest. It cant be more clear than this. But even that didnt last long. It is very safe: There is no evidence fluvoxamine is harmful and led to a worse outcome. That was a lie. He immediately tweeted an offer to give anyone $1 million if they could win a debate with him about vaccine deaths. Immediately after the results of the first fluvoxamine trial were releasedbut before they were published in a peer-reviewed journalhe wrote a post on Medium.com called The Fast, Easy, Safe, Simple, Low-Cost Solution to COVID That Works 100% of the Time That Nobody Wants to Talk About.. If you cant get a prescription for COVID, then perhaps you have OCD? Fluvoxamine works on hospitalized patients too, but no US hospital will let you use it (sound familiar? Ive used it personally at 50mg twice a day and experience no adverse events at all. Boulware disputes that, and says that although Kirschs funding was important, his statements about drugs and vaccines have proven problematic. Thats pretty typical, but your mileage may vary. Jeffrey Morris, director of biostatistics at the University of Pennsylvania Perelman School of Medicine, has made debunking Kirschs claims something of a hobby. It could do nothing. Its the gold standard of medical evidence. The agency quickly slapped down the comments from Kirsch, a tech mogul with a fortune once estimated at $230 million, even as the claims triggered a flurry of false social-media posts attributing. Medicine has been transformed to doing whatever the NIH/FDA says, regardless of how many lives will be lost. Steve put in $1MM of his own money and . Ivermectin and fluvoxamine have been confirmed in Phase 3 trials. Everyone says "we need more data" to show fluvoxamine works for COVID. He started 7 high tech companies, two with billion dollar market caps. Medicine has been transformed to doing whatever the NIH/FDA says, regardless of how many lives will be lost. This is the gold standard of evidence based medicine. Jeffrey Glenn, an infectious disease professor at Stanford University, calls the inaction on the current evidence on the table "criminal.". The sooner you start, the better the outcomes. fluvoxamine The fast, easy, safe, simple, low cost treatment for COVID that has worked 100% of the time to prevent hospitalization that nobody wants to talk about We now have a viable solution to reduce COVID hospitalization and mortality; Read More fluvoxamine Got COVID? What's even worse is that a third of recovered patients from COVID will return to the hospital within 5 months and 1 in 8 die. Yeah, its possible, he told mehe also says that he has regularly seen Kirsch manipulate evidence so that it seems to support claims that are, in reality, baseless. Thats what creates some of these heroes.. Fluvoxamine public data repository: The fluvoxamine public repository has all the documents related to fluvoxamine for COVID, including the RCT, RWE, observational studies and a link to the 1 hour lecture on serotonin and fluvoxamine. saying that the per-protocol analysis was arbitrary and other excuses. this is NOT about the science. Steve Kirsch -Executive Director at COVID-19 Early Treatment Fund Ivermection study - One .2mg/kg dose a week for prevention "100% success rate whereas those doctors taking placebo had a 59%% infection rate not a typo 237 of 400 docs on placebo got infected vs. 800 docs on Ivermectin none got infected" Antivirals Also, for people who cant tolerate fluvoxamine for whatever reason (nausea, jittery, etc), this is the alternative. Instead, the government prefers to fund and promote new, proprietary drugs and vaccines, he says. Pretty much nothing changed when the Phase 3 trial confirmed fluvoxamine worked. Proven in clinical use all over the world. As a health care journalist, I started off firmly in the wait-and-see camp on mRNA vaccines. So why would we wait when lives are being lost? The paramedics will think you are on drugs. ALWAYS check with your doctor and report any medications you are taking before or plan to take after you start taking fluvoxamine. Some countries dont have fluvoxamine so this is the alternative. All can merit a fluvoxamine prescription based on traditional diagnoses. Dosage there is 30mg once a day. Who knows, Morris replied. If you cant lay off the java, then try fluoxetine (Prozac). In three phone conversations, as well as dozens of emails, his responses to questions about claims in this story were imprecise or constantly changing. The ongoing battle between social-media companies and covid-19 misinformation pushersincluding US president Donald Trumpstepped up again this week thanks to a new viral video. Its sad, but its true, he told me. But the confusion provided a fertile breeding ground for skeptics. So when a group of scientists applied for an EUA for fluvoxamine, what did the FDA do? After boosting unproven covid drugs and campaigning against vaccines, Steve Kirsch was abandoned by his team of scientific advisersand left out of a job. When the pandemic started, he created the COVID-19 Early Treatment Fund (CETF) to fund researchers working on repurposed drugs including fluvoxamine which reduces death from COVID by a factor of 12. So how did a man once intent on furthering science become a source of misinformation that undermines the very research he funded? I am not aware of a single case where taking the made things worse, e.g., person was doing fine BEFORE the drug and symptoms worsened after taking the drug. I took it myself at that dosage and noticed zero side effects. Most recent articles first. But how many did it help? Compulsive hand washing? Dose escalation studies in lupus patients and in rheumatoid arthritis patients established that 800 mg per day for life and 1,200 mg per day for 6 weeks are extremely well-tolerated. You will be wired for 24 hours if you dont heed my advice. Online. Some countries dont have fluvoxamine so this is the alternative. Every earlier study of fluvoxamine (such as observational studies) showed it work and the mechanism had been shown. What has alarmed many of the scientists associated with CETF, though, are Kirschs reactions to the work hes fundedboth successes and failures. Also, this drug is only prescribed by psychiatrists so most doctors have no experience whatsoever with the drug. . If the drug is started right after symptoms, weve seen 100% prevention in hospitalization. My favorite dosage is 50mg twice a day for 14 days. My website www.skirsch.io has tons of info on fluvoxamine with all the links. It is currently approved for treatment of depression and obsessive compulsive disorder (OCD). Three of the four outpatient trials have been reported out: all were successful. Molnupiravir followed patients for only 30 days because they know the drug is dangerous. Some people report mild nausea while on the drug (stops when stop the drug). How can the FDA say a drug which meets the gold standard of evidence has insufficient evidence? Here is the latest version. They were all given the drug soon after symptoms and the placebo group was pure in that they were not taking any COVID drugs. Or just depression about the vaccine mandates? In September, Kirsch emailed Morris asking him to estimate the maximum number of deaths caused by vaccines. If you take fluvoxamine, please avoid caffeine while on the drug. He felt like he in good conscience had to speak out about covid, and so he made the decision to separate himself from M10, says Char, who has known Kirsch since the 1980s. Compulsive fiddling with your mask? Can I see your risk-benefit analysis?. Nobody who took the drug got sick at all, most all wanted to return to work within 3 days after starting treatment. But as Kirsch has clashed with the experts he initially surrounded himself with, hes grown increasingly close to others who share his perspectives on vaccineswho have, in turn, provided a large and receptive audience to his claims about a fluvoxamine conspiracy. Since FLV is a safe drug, it should have been widely discussed with patients that there is virtually no downside and a huge reduction in hospitalization if the drug is given early. Thirty minutes past the end of our scheduled time, he dropped his phone in the cupholder of his Tesla so that he could keep talking while he ran an errand. Think about it Molnupiravir has a 50% risk reduction whereas fluvxoamine is over 90%. I fully expected both organizations to do absolutely nothing. . Hes very convincing. He applied the drug to a large COVID outbreak at Golden Gate Fields just days after the Lenze trial was published. The study was also featured on 60 Minutes. Almost 2.5 million people signed up to Dr. B with the promise of getting leftover vaccines. Thats why they didnt change their recommendation when the Phase 3 trial was published in Lancet. The NIH picks the drug that makes the most money for the drug companies regardless of long-term safety Molnupiravir! My publicly shared concerns regarding the safety of the COVID-19 vaccines may have had a negative impact on my company, M10. That was a lie. He started a covid-19 vaccine company. If you wanna find someone to debate me for ten thousand dollars, or a thousand dollars, Im happy to do that, just for your benefit.. Every year, we pick the 10 technologies that matter the most right now. Fluvoxamine works on hospitalized patients too, but no US hospital will let you use it (sound familiar? Physicians who use the drug for COVID now swear by it. You will be wired for 24 hours if you dont heed my advice. The group who declined the drug were very sick with 12.5% requiring hospitalization and one died. If you are experiencing any odd adverse reactions, youll need to consult with your doctor ASAP. I fixed the link to the fluvoxamine article. The rest of the board soon followed. , or the patient is simply sensitive to the drug (50mg twice a day can be too much for some people). Seftel was able to duplicate the 100% protection from hospitalization and death in the treatment group, vs. a 12.5% hospitalization/death rate for the No treatment group. Generally, at 50mg BID x 14, it is very tolerable as long as the patient is instructed to lay off the caffeine. But they dont want their names used. Personal life. When you need to characterize me, you need to say that Steve Kirsch doesnt go with majority votes on interpreting data, he told me when I asked about his views on ivermectin, which he insists is a silver bullet against covid. Their willingness to lie did. Doctors are afraid that even with a 37-year safety record of this drug, that something will go terribly wrong and they will be blamed. Why not fluvoxamine? It is in a class of drugs known as selective serotonin-reuptake inhibitors (SSRIs), but unlike other SSRIs, fluvoxamine interacts strongly with a protein called the sigma-1 receptor. . Hes now outlived his initial prognosis by several years. No long haul symptoms if you start the drug ASAP after first symptoms. In some cases, youd want to taper down the dosage. . It works best when it is given early, as soon as symptoms start. CETF founder Steve Kirsch accepted an invitation to discuss the findings on a weekly . Please read and agree to the disclaimer before watching this video.. Steve Kirsch On COVID Early Treatment and CensorshipSteve Kirsch is an entrepreneur and . CETF funded David Boulware's trials on hydroxychloroquine and the Phase 2 and Phase 3 fluvoxamine trials, among many other research projects. Note that some of these articles are inaccurate. Things took a final and dramatic turn once Kirsch started claiming the government was covering up vaccine deaths. Expect similar things to happen when Eiger applies for an EUA for interferon lambda, a drug with a 89% efficacy in phase 3 trials. In fact, he was unwittingly the source for one of Kirschs figures. Dosing. Elsewhere he has said he began questioning vaccine safety after an unnamed Twitter follower told him several family members died after getting their shots. He has been a medical philanthropist for more than 20 years. A very short op-ed arguing for using fluvoxamine against COVID. The NIH wrote a bullshit rejection because the FDA told them not to approve it. 4000fluvoxamine750 Theres nothing there.). Fluvoxamine, Proxalutamide, and Ivermectin: 100% success I'm very bullish on two drug combos since it is rare for Read More The best COVID treatments for hospitalized patients Seven treatments for hospitalized COVID patients with very high success rates. The group who declined the drug were very sick with 12.5% requiring hospitalization and one died. Thanks for working tirelessly to help others. Kirsch is a serial entrepreneur who has spent decades pitching the next big thing, whether optical mice (Mouse Systems), document processing (FrameMaker), search engines (Infoseek), digital security (OneID), or e-commerce (Propel Software). While these are stunning results, less than a dozen doctors in the US are prescribing fluvoxamine today. (The fund borrows its nonprofit status from the 501(c)(3) Rockefeller Philanthropy Advisors, which managed its money until it quit, according to the Daily Beast; neither organization is related to the Rockefeller Foundation, which supports Technology Review's reporting on covid.). The differences are obvious to untrained eyes. . One of the drugs, Fluvoxamine, showed a 30 . He said of his study, This is the most extraordinary effect Ive seen in my 25 years practicing medicine.. But even she was drained by Kirschs constant attempts to override the data. Fluvoxamine is a selective serotonin reuptake inhibitor (SSRI), a class of anti-depressants, mostly prescribed for people suffering from an obsessive-compulsive disorder. Both drugs have compelling data that is hard to explain if the drug doesn't work. I mean, he really, truly has a heart of gold, Char told me. . All the researchers are convinced the drug works. It was approved by the FDA in 1994 and has been used in millions of patients worldwide. By March 2020, hed settled on the idea of searching for covid treatments in the pre-existing pharmacopeia. Steve Kirsch is a high-tech serial entrepreneur based in Silicon Valley. The 5 observational studies is icing on the cake. After publication of the recommendation in December 2021, the NIH did absolutely nothing change their recommendation. I couldn't agree more. Online Status. Mr. Steve Kirsch - A philanthropist and former Silicon Valley tech executive. Since then, he has continued to promote fluvoxamine, along with ivermectin and hydroxychloroquine. The claim that the spike is toxic, that came directly from the [DarkHorse episode]. Ive talked to doctors who are extremely familiar with the drug and all the trial results and they would prescribe it to their patients. Its really, really common for a small effect, something that looks exciting, to be a statistical fluke when you look at a larger population. Seftel used a 50mg BID dosing for 14 days which was one third of the max dose used in the Lenze study. Fluvoxamine has a 40 year safety track record. Fluvoxamine (Luvox) is a Selective Serotonin Receptor Inhibitor (SSRI) that is clinically indicated for OCD in children, and can be used off label for depression. After two weeks (since it was a tight knit community, everyone could see what was happening to the two groups), every track worker who got sick with COVID, demanded the drug. Yes, these were successes, but the successes could have been bigger if we had really paid attention to marketing. 707. NIH and WHO refuse to acknowledge it works since it will cause vaccine hesitancy if it is known that there is a drug that turns COVID into a mild disease. Fluvoxamine is a very safe drug on market for 37 years, tens of millions of people have taken it, no record in scientific literature of anyone dying on overdose, and according to doctors that know the drug the best, about as dangerous as taking a Tylenol. The evidence is solid. 1:49 Di scl ai mer: T he vi ews expressed i n t hi s art i cl e are my own personal opi ni on based on my 1, 000+ hour st udy of cut t i ng edge . Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month Death Signal, Mystery Clots Embed 7.76K 31 'This Has Cost Millions Of Lives': Steve Kirsch On Suppression Of Repurposed Drugs And A Spike In Deaths 5 Months After Vaccine Rollout By Jan Jekielek American Thought Leaders / The Epoch Times November 24, 2022 Show more Over the last 18 months, the fund has granted at least $4.5 million to researchers testing the covid-fighting powers of drugs that are already FDA-approved for other diseases. We don't know why the NIH panel is ignoring fluvoxamine and we aren't allowed to find out. Items included in the Television News search service. He is frequently brash and interruptive, peppering dire warnings about vaccines with veiled aspersions toward Anthony Fauci and vague references to influential people who agree with him in private but cannot speak publicly. After I ended the Zoom meeting, Satterfield called me to apologize for cutting us off. His appearance on an episode of anti-covid-vaccine, pro-ivermectin pundit Bret Weinsteins DarkHorse podcast, alongside Robert Malone, a prominent source of vaccine misinformation, introduced Kirsch to followers of the intellectual dark web, who have since embraced him as a fellow truth-teller. Fluvoxamine for COVID-19 summary Steve Kirsch Executive Director COVID-19 Early Treatment Fund stk@treatearly.org 650-279-1008 Google Docs This is a more comprehensive look at the key evidence supporting fluvoxamine: Fluvoxamine for COVID-19 I agreed to do it partially because I respect Bob [Siliciano] so much, and partially because I thought the concept was excellent, said former board member Doug Richman, a prominent HIV drug researcher at the University of California San Diego and former member of the funds scientific advisory board. 90,000 people don't have to die in the next 3 weeks. It never was. This site requires JavaScript to run correctly. This post was written to memorialize the corruption. It is about following orders and making money for the drug companies and protecting the doctor from liability and losing his medical license. David Boulware, a researcher at the University of Minnesota, received $125,000 to test the drug against covid. This advice is now outdated. So the drug had no chance of working (since there were no events), so the trial was stopped for futility, NOT because the drug doesnt work. If you do have a side-effect, it is usually mild nausea which goes away when you stop taking the drug. I took it myself at that dosage and noticed zero side effects. So take the lowest likely effect size * 60% success rate and you are looking at an expected 45% reduction in death which is clearly better than a 0% reduction. Today, we are letting people drown and we are not even telling them there is a life preserver they can ask for today with compelling evidence that is under consideration by the life preserver safety group. . How covid-19 conspiracy videos keep getting millions of views. Now they turn to Rust. I believe they made the right decision and we should be rushing to follow their advice. He was recently featured on 60 Minutes which highlighted his . Since FLV is a safe drug, it should have been widely discussed with patients that there is virtually no downside and a huge reduction in hospitalization if the drug is given early. [4] Steve Kirsch - Silicon Valley Philanthropist Shares Review of CDC Data: COVID-19 Vaccine Associated with 100X Deaths Compared to Influenzas [5] Steve Kirsch - FOIA Document for Vaccine Discussion as to mRNA-based Vaccine Safety Signals Added 12th August 2021: Paper reviewing the evidence and mechanisms of action for fluvoxamine: Lenze Phase 2 RCT published Nov 12, 2020: Seftel RWE trial that confirmed the Phase 2 trial published Feb 1, 2021. He prefers iconoclastic approaches, whether by directly funding asteroid detection or advocating for nuclear power to combat global warming. All the medical journals refused to publish the meeting notes (rejected by 6 journals). The infectious disease scientists lied to me. It will be months before enrollments are complete. Its whether Merck can make a killing that matters. The FDA is will take months to deliberate on the fluvoxamine EUA application that we submitted on January 29. Then he hosted a superspreader event. It doesnt get any better than this. Its not about the science. ICER, a non-profit known as the nations drug pricing watchdog, did a review of the evidence and determined that fluvoxamine evidence is superior to Molnupiravir. Drug researchers at Washington University in St. Louis reached out to Kirsch looking for $67,000 to finish a very smallbut placebo-controlledtrial. Refresh. As Kirsch has gone deeper into the anti-vaccine scene, many professional associates have increasingly distanced themselves from him. On his blog, Covid-19 Data Science, he has extensivelyand mercilesslyunpacked Kirschs evidence for the vaccine death claims. See this Wall Street Journal op-ed. If it isn't fluvoxamine preventing hospitalization and long-haul COVID, then if you find what it is, you win. How I recommend people treat COVID and the fascinating backstory of how fluvoxamine was discovered. The. The NIH never did a risk benefit analysis of this drug. The medical community did nothing (with a few exceptions like Dr. Seftel). Here's why. Boulwares trial was part of a wider movement to bulk up the evidence base underlying standard covid treatments, and one of several trials that found no benefit to using hydroxychloroquine. Entrepreneur Steve Kirsch who holds an early patent for the optical mouse decided to get involved in treating Covid. And, according to three members of CETF's scientific advisory board, he put pressure on them to promote fluvoxamine for clinical use without conclusive data that it worked for . They knew in advance it was coming and on the day the paper was published they ignored it entirely. Infoseek lost out to Yahoo; it had a chance to grow bigger, but it didn't. Quick Summary . Fluoxetine is just as effective. skirsch.io Steve Kirsch Home page. . Every earlier study of fluvoxamine (such as observational studies) showed it work and the mechanism had been shown. . So probability of successful Phase 3 can be estimated to be over 99.99% since there are tens of thousands of phase 3 studies. I will . Its all about NIH saying it is OK. Medicine today is driven by government opinion, not science. It is about following orders and making money for the drug companies and protecting the doctor from liability and losing his medical license. Other drugs in this class include Prozac (fluoxetine), Zoloft (sertraline) and Paxil (paroxetine). Another CETF grant, though, yielded far more exciting results. His latest startup, M10, is a spin-off of a spin-off that sells a blockchain for banks. Skirsch.io traffic volume is 1,957 unique daily visitors and their 3,914 pageviews. Steve calls himself a "medical philanthropist" who says "the most important thing to me is saving lives." In . are all super cheap, effective, and available without a prescription. reach out to us at This give another 50% of benefit. We dont want to feed the anti-vaccine trolls, so we actively suppress clear scientific data. How I recommend people treat COVID and the fascinating backstory of how fluvoxamine was discovered. The race to find covid-19 drug treatments that actually work, The antimalarial drug Trump took for covid might actually be dangerous. It was 25 years ago yesterday that Andrew Wakefield launched the modern iteration of the antivaccine movement.In doing so, he laid down a template that antivax quacks today still follow. We don't know why the NIH panel is ignoring fluvoxamine and we aren't allowed to find out. Steve Kirsch is an inventor of the optimal mouse, a Silicon Valley millionaire, and an MIT alum (Class of '80). Fluvoxamine is an inexpensive drug that has been in use for 37 years and has been used by an estimated 10 million people. He has a BS/MS in Electrical Engineering and Computer Science from MIT. Note: normally I have lots of hyperlinks to all the sources, but Im pressed for time. The drug was FDA-approved more than 65 years ago. CETF funded David Boulware's trials on hydroxychloroquine and the Phase 2 and Phase 3 fluvoxamine trials, among many other research projects. If you have trouble getting a prescription, perhaps you have OCD? At that dose, no side effects were reported for his patients (I know of only one person who had mild nausea at that dose) and everyone reversed out their symptoms in an average of 3 days. Kirsch said that his attempts to promote fluvoxamine are being curtailed. Most doctors wont use it until NIH greenlights it, no matter what the science says. Kirsch is a serial entrepreneur who has spent decades pitching the next big thing, whether optical mice (Mouse Systems), document processing (FrameMaker), search engines (Infoseek), digital. There are reports of people who cant tolerate the drug, but they stop using it and nothing bad happened. Its board told him that if he wanted to remain part of the company he would have to stop making public anti-vaccine statements. Steve Kirsch. A video presentation by Steve Kirsch, Executive Director of the Covid-19 Early Treatment Fund. This suggests that a 50mg BID loading dose for day one, followed by 50mg QD dose for the following 13 days should also be quite effective. Ivermectin has a very high quality systematic review, the highest possible level in Evidence Based Medicine. Worst case, if we ignore all additional evidence so the average is a 60% pass rate. Get your prescription in advance of getting COVID. And FrameMaker is still a niche product. And while Morris believes that all claims about vaccine safety should be properly vettedIs it possible theres another rare side effect of the vaccines that we havent figured out yet? The WashU Phase 3 study hasnt been disclosed yet, but they had compliance problems with their patients this time around (phase 2 was local so the patients got the drug early and also were very compliant and the placebo group was truly taking nothing). The most stunning study of fluvoxamine ever done was at the Golden Gate Fields racetrack in November 2020, right after the WashU trial was published in JAMA. It could do nothing. Flavio Cadegiani and Steve Kirsch's studies didn't make the cut. Thats why they didnt change their recommendation when the Phase 3 trial was published in Lancet. The U of M's study focused on three common drugs: ivermectin, metformin, and fluvoxamine. This was shown to be very tolerable (no side effects in 99% of patients) and extremely effective (no hospitalizations and death if you start it ASAP after first symptoms). , a non-profit known as the nations drug pricing watchdog, did a review of the evidence and determined that fluvoxamine evidence is superior to Molnupiravir. Reason is the hospital gets release from liability if they follow NIH guidelines. Hes also recently increased the number of Americans he claim have been killed by the vaccine from 25,0000, to 150,000, or even as many as 250,000 Americans. By Steve Kirsch in fluvoxamine Feb 14, 2021 The case for fluvoxamine for treating COVID-19 A very short op-ed arguing for using fluvoxamine against COVID. The babys brain was split in half, and it was just covered with blood. The track management was so impressed, they asked for prescriptions. He pushes fluvoxamine, an anti-depression drug which despite doing very well in covid treatment studies has been strangely neglected. So there were too few events in the placebo group and they werent recruiting fast enough. The reason that it isnt used is because the medical community ignores evidence-based medicine principles. So it was both obvious and convincing the difference between the groups to the workers and the track management. This 1/6 of the dose the FDA has approved for OCD (the labelled indication for fluvoxamine)! We are ignoring the advice of the KOL group and doing nothing. We look for advances that will have a big impact on our lives and break down why they matter. In it, he claimed mRNA vaccines kill one in 5,000 recipients and dramatically increase the rate of miscarriages. Steve Kirsch, current director of the Covid 19 Early Treatment fund is an MIT alumni who has made a career as a tech entrepreneur. Summary of key evidence. Our in-depth reporting reveals whats going on now to prepare you for whats coming next. To date, the #1 drug with the most evidence to make a significant difference, without any doubt, is fluvoxamine. By the beginning of September, he was no longer the companys CEO, replaced by his co-founder, Marten Nelson. I have all of these on hand and I load up on vitamin D3 every day.
Brandon Nakashima Ethnicity,
Articles S