In rare cases, someone may not be able to produce hormones on their own. Subjects were HPTA shutdown with T cyp injections, LH/FSH were close to zero in a couple of days. Any TRT dose shuts down HPTA, causing LH/FSH>zero. Your IP: Would you just stop, or run an AI afterwards? Both primo and dianabol will shut down HPTA. Natural testosterone production relies on a balance of hypothalamus hormones including gonadotropin releasing hormone (GnRH), pituitary hormones including luteinizing hormone (LH), and the testicles where testosterone is produced. All HCG does is trick your balls into thinking it's still producing LH, but it's not. That could be due to a problem, hypogonadism, or alternatively could be because you're taking exogenous testosterone at an amount that is causing your body's natural production to stop working because it sees the high level and . Dec. 6, 2011 -- The Food and Drug Administration and the Federal Trade Commission issued warning letters today to seven companies that market over-the-counter weight loss products containing . If he was on for a long time I would also do a one time injection of triptorelin. I stopped so I could dial in my test and adex. Is there any down side of taking hcg monotherapy 500 IU every week? One of the big goals of post cycle therapy is to get your hormone balance back on track. For the sake of my eyesight I will not be running clomid or nolvadex. When a man is HPTA suppressed for any reason they need to take HCG for just this reason. An hCG beta blood test is much more sensitive than an HPT, and can detect pregnancy as early as 10 days after fertilization. Looking for some advice or confirmation. PCT Need to look into dosages and durations due to extended length of shutdown but standard Nolva and Clomid. Normal total testosterone production for a healthy male is about 500-600ng/dl (too many are in the 200-350ng/dl range due to environmental estrogens alone), but some AAS users push the levels into the 2000-3000ng/dl plus area. LH/FSH levels will have to rise as well as testosterone levels to a certain amount before you can discontinue. This all depends on your initial diagnosis. Recent Yearly Bloodwork- some help please! While on TRT therapy, you are shutting down your natural testosterone production. . This is called the Hypothalamus-Pituitary-Testicular axis, or HPTA. is my hemo and hematocrit crazy high or ??? Human Chorionic Gonadotropin, or hCG, production begins approximately 8-10 days after conception when the embryo starts to burrow itself into the lining of the uterus. Injecting 250 mg every two weeks exposes the body to higher peaks that injecting 125 per week. Your long-term satisfaction will be all the greater. . As a result of all of this excess testosterone floating aroundthe body, there is a lot of aromatization to estrogens and an overabundance of androgen receptors of the hypothalamus being over-stimulated. Because of the consistent sub-optimal readings Ive gotten over the last few years Im now attempting to do a restart since the last time I did one it seemed to go pretty well and that was 4 years ago. Makes sense, the argument with the battery analogy also makes sense. Have tried before and didn't feel any subject benefits but was doing a small dose of 125iu per day. anybody got a woman pregant here while being on TRT 1+ year? In today's media-hysteria-managed environment, athletes, supplement companies and drug dealers alike are seen in the same shady light. It is important for the HCG administration to have been completed with 6 or 7 clear days before the onset of PCT in order to avoid inhibition of the Nolvadex and/or Clomid therapy. Or does only the part that controls LH and FSH shut down? Email today and a Haz representative will be in touch shortly. But this combination only helps clean up the effects of the Estrogen Negative Feed-Back Loop leaving the Androgen Negative Feed-Back Loop unaffected. There may be cases where a patient cannot maintain adequate testosterone production on their own after discontinuing hormone supplementation. With that being said Im one month into running HCG which I was planning on running for 8 weeks total (800 ius 3x per week) and my question is what is the best way to come off of the HCG? Open to hearing other thoughts but if the consensus is to just stop the HCG and levels will bounce back on their own, I can do that. .hide-if-no-js { . I believe the most we can say with some degree of authority is HPTA dysfunction Steroids doesnt shrink your penis but depending on your cycle and the drugs you use they will shut you down. J Steroid Biochem Mol Biol. But there isn't a right answer. Post cycle therapy (PCT) is a critical action to take and one that deserves just . 5 I have 2 boxes, each with 3 vials containing 2000iu. In the new millennium performance enhancement through supplementation became a science. 3) HCG 5000IU twice weekly. On top of what's already been mentioned: If the reason guys took time to recover from a cycle of AAS was simply HPTA shutdown (negative feedback) from a decrease in LH/FSH, then the mildly supraphysiological levels you can get from using SERMs may arguably accelerate that process, though natural LH/FSH levels recover very rapidly as it is, and cell (if not receptor) I feel now it would be better to do low dose hcg mono or in combo with trt.. question. You can speed this up (and you should) by taking a combination of HCG, Nolvadex and Clomid. JIMO - Because you are using exogenous Testosterone your HPT Axis is already suppressed so in essence your negative feed back loop in in full gear. I believe in the whole genetic limit though; some people can hold more muscle than others; for example take a look at Chris Jones; dude is 5'6-5'7 185lbs shredded(bbc genes); and then you got people who are 5'10 that can get above a 180lbs lean no matter how hard they try. Give us a shout. Sundays - Closed, 8642 Garden Grove Blvd. The one size fits all theory does not apply and you must get lab work to see whether your testicles are functioning to the degree in which they will be responsive to the LH/FSH that your pituitary will secrete to stimulate endogenous testosterone. Hmmm, still nothing to "positively" affect the Androgen Negative Feed-Back Loop. The leydig cells stop producing test, until homeostatis is met, and testosterone has a higher ratio to estrogen than it currently has. If HCG use at 250iu's e3d or twice a week is good to keep your boys up and running which in theory prevents any shutdown of the HPTA, why can't HCG be run for extended periods of time? Like all things we really like in life, there is a series of checks and balances that keep things in control and limit the amounts of good stuff we can have (like girlfriends). But it can help you avoid avoid hormone withdrawal symptoms for a more comfortable transition. Copyright 2012 - 2022 Evolutionary.org. display: none !important; Click Here For The Top Selling Anti-Estrogen Products. Many AAS users know that by decreasing the amount of circulatory estrogen, they are also able to somewhat decrease HPTA down-regulation. 08-22-2018, 01:52 PM #2 The result is a dramatic unhealthy reduction, or even shut-down, of the HPTA and girl status for the owner of the saggy-sack problem. Watermelon Breeze Tropicana, I was hoping that HCG would help convert cholesterol to pregnenolone to support adrenal productions to ensure proper cortisol reaction to the stimulus. Roselli CE, Resko JA, Stormshak F. Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, Oregon 97201-3098, USA. Many progressive testosterone physicians prescribe HCG for men to take during testosterone replacement therapy to help maintain testicular volume and fertility. Because sex drive and sexual function are closely tied with Testosterone production, low Testosterone levels can lead to ED and decreased libido. Very long term TRT (20+ years) - risk of liver cancer? Not all steroids do cause shut down of the feedback mechanism. It also has the ability make more thyroid hormones and other fat burning substances than you could ever reasonably want (never met a reasonable bodybuilder but I did hear of one once). No action should be taken solely on the contents of this website or our testimonials. The whole idea of supplementing with steroids is to override the mechanism for negative feedback. if so, do the benefits of total HPTA shut down (from lifelong TRT), outweigh the negatives of having low T? . This is the responsibility of an enzyme called aromatase that is present pretty much everywhere in the bodyeven the brain around the hypothalamus (remember that). Hi: By most accounts, nandrolone is an extremely mild steroid. seven I would like to see the results from the same test subjects using the 50mg 3-OHAT/ATD proprietary blend with the addition of Agaricus bisporus extract (white button mushroom from a specific region) and 7b-hydroxy-DHEA. To still maintain healthy functioning and have high GH and IGF-1 levels supplementation of a GH releaser such as a peptide combination is most necessary.(11)(12)(13). When discontinuing a long-acting injectable ester, such as cypionate or enanthate, therapy to stop TRT is usually initiated roughly five days after the last injection, as the hormone levels start to fall. In addition there is some degree of decrease in estrogen activity throughout the rest of the body as well for the same reason. Clomiphen Citrate is the generic name for Clomid which is a fertility drug used to stimulate ovulation in women and increase sperm production in men. JavaScript is disabled. Naturally there is a dose dependant issue here which is a supplemental oxymoron: Low bioavailability means higher dosages needed, that in turn result in greater amounts of AT being converted to the feminizing estrogens 6-keto-estrone and 6-keto-estradiol. Can that be done? By Posted on Mar 10, 2021. does hcg shut down hpta. This is the proper protocol for a successful normalization, this is the program that allows for you to transpose from exogenous testosterone replacement therapy to be all natural WITHOUT testosterone deficiency and the living hell many endure without being able to restore your own levels. (If you are paying attention and focusing a little here, I am sure the real point of this article just hit you). Mechanism of Suppression. It is this hormone that is measured by early pregnancy tests and if present, will return a positive result. Most guys use hcg during a cycle to keep the testicles their normal size, other guys use it right after a cycle to get their testicle size back and to stimulate them into producing testosterone. Maybe others can chime in on this with their experiences - but this was mine. Anastrolzole is a generic name for the drug Arimidex. Their may be little you can do about the SHBG, so any testosterone gains you make will quickly be bound up to SHBG and deactivated not allowing your FT to increase enough. 1992 Oct;43(4):281-7.In vitro potency and selectivity of the non-steroidal androgen aromatase inhibitor CGS 16949A compared to steroidal inhibitors in the brain. Thus estrogen produced by a cow (which is present throughout the meat) is a xenoestrogen. An hCG beta blood test is much more sensitive than an HPT, and can detect pregnancy as early as 10 days after fertilization. These authors would consider treatment with CC 25 mg daily with hCG 3000 IU every other day for 3 months, with a reassessment of the HPG axis and physical exam to ensure improvement before VR. You are using an out of date browser. If youre thinking about stopping TRT, there is a protocol that can help prevent hormone withdrawal symptoms by restoring your own hormone production. 34.245.32.234 If you want to discontinue TRT safely with limited side effects, Defy Medical can help. One more thing if the Hcg helps to get me back up and running can it shut my HPTA again. We respect your privacy and take protecting it seriously, Captcha:* * My HPTA has been screwed up for a few months now and I tried Sustain Alpha which doesn't seem to be working. Interset Research and Solution; does hcg shut down hpta Reply. Welcome to ExcelMale.com, the leading and best-moderated mens health forum focused on increasing health, potency and productivity in men. This is an aromatase enzyme inhibitor that decreases conversion of susceptible androgens into estrogens. #4. Pregnenolone being a very important neurosteroid and supports healthy brain function, modulates NMDA receptors and has been proven to reduce negative effects induced by schizophrenia (this example to show how powerful it is, not that you have schizophrenia). It makes since that HCG will suppress LH release due to the increase Testosterone production effecting the negative feedback loop. However, the Androgen-Negative-Feed-Back-Loop still remains the main limiting factor. I am currently beginning my second cycle and I am a little worried about shutting down my hpta. A cycle of steroids completely changes the functioning of your natural hormone system. Do consult a proper endocrinologist for information. All steroids act similar to testosterone in the body, therefore they all shut you down. Like LH this hormone is also sent out from the pituitary and signals the Sertoli cells inside the testicles to make sperm. HPTA stands for hypothalamic-pituitary-testicular (or sometimes gonadal) axis. Any outside amount will shut you down if taken for an extended time period. THAT is HPTA Supraphysiological Overcompensation. The increased estrogen sends signals that there is to much conversion, while your Hypothalamus sends signals that too much estrogen is in your system, so the secretion of LH and FSH is halted. Hpta Restart protocol/power pct by Dr. Michael Scally. Take precautions and aim to achieve. That is ugly. Home; Products; About Us. I never said I didn't agree with you . It works by blocking more powerful and active estrogens from merging with the hypothalamic estrogen receptors. During this period it is important to make sure your body is filling up with essential base hormones such as DHEA and Pregnenolone as well. (No joke!) During the pre-administration period we tested for Total Testosterone, Free Testosterone and Estradiol, then tested again at 14 and 42 days. Many doctors now refer to tongkat ali as being "herbal HCG" or herbal clomid but its perhaps better more like clomid this HCG because it forever stimulates your HTPA and never shuts it down like tribulus or HCG can. besides Fertility, is there any down stream or related consequences on someones health with a shut down HPTA for 50-60yrs? 1986 Oct;25(4):593-600. JIMO you are 100% correct in this statement: "I was hoping that HCG would help convert cholesterol to pregnenolone to support adrenal productions to ensure proper cortisol reaction to the stimulus". The whole idea of supplementing with steroids is to override the mechanism for negative feedback. HCG has been a utilized as a "partial cure" for the shut-down of the hypothalamus-pituitary-testes-axis (HPTA). F. However, with a smart dosing protocol and a sensible dosage, suppression will be very minimal and a non-issue. On the other hand tongkat continues to raise the bar higher and higher in time as you continue using tongkat. = In the 90's, a few viable performance-enhancing options such as creatine monohydrate and whey protein made their way into the market thus finally offering health and performance oriented alike something of statistical value. 1500/7=214. Blood test results after 6 week clomid therapy from HPTA restart. Schneider Electric Inside Sales Salary, Monday - Saturday 8:00 am - 5:00 pm But we will save that for future articles. HCG sees use in some PCT but that is a misconception because HCG works quickly and restores testicular volume giving the appearance of treatment however in the long run does not properly restart your HPTA. Answer (1 of 3): From my research, any amount of exogenous testosterone. The largest testosterone increase was in Group . In fact, it's probably the least estrogenic of all the steroids . The Agaricus bisporus extract because the right method of extract provides some very effective site-specific aromatase enzyme inhibition, and the 7b-Hydroxy-DHEA because it is preferential physiological base compound for many good things. The mean receptor level reached a nadir which was 5--10% of that in the control testes, 3 days after the injection, after which it gradually . I'm 6'2". Prenatal inhibition of aromatase activity affects luteinizing hormone feedback mechanisms and reproductive behaviors of adult guinea pigs. I've been on TRT for the past 12 years due to bilateral testicular cancer. Seemed to be fine. . Keeping this in mind when starting a cycle and planning a PCT is vital. Recent Yearly Bloodwork- some help please! Thanks guys, I will properly reincorporate HCG soon. I was afraid that could be the case but I figured since I did run a bunch of cycles in the past with no HCG that maybe it would stimulate the testes to a higher point as a last ditch effort.
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