https://www.census.gov/programs-surveys/popest/data/tables.2019.html, https://www.cdc.gov/nchs/data/statnt/statnt20.pdf. Each CI represents the remaining variation in observed weekly incidence rates and resulting incidence rate ratios. SARS-CoV-2 Infection and Hospitalization Among Adults Aged 18 Years, by Vaccination Status, Before and During SARS-CoV-2 B.1.1.529 (Omicron) Variant Predominance - Los Angeles County, California, November 7, 2021-January 8, 2022. Questions or messages regarding errors in formatting should be addressed to Claudia Corwin, MD, MPH, an occupational medicine specialist and associate director of the University Employee Health Clinic, breaks down the biggest differences between delta variant COVID-19 infection in vaccinated and unvaccinated people. New variants combined with a reduction in masking and other non-pharmaceutical interventions may also lead to more transmission, which can in turn lead to more deaths. that during the omicron wave, adults who had received two doses of the Pfizer/BioNTech or Moderna vaccines had a 79% lower risk of dying or needing a ventilator if hospitalized with COVID-19, compared with unvaccinated adults. Each CI represents the remaining variation in observed weekly incidence rates and resulting incidence rate ratios. Fericean RM, Oancea C, Reddyreddy AR, Rosca O, Bratosin F, Bloanca V, Citu C, Alambaram S, Vasamsetti NG, Dumitru C. Int J Environ Res Public Health. However, only 14% of adults overall and 31% of older adults (65 years and older) have received the latest bivalent boosters. Pediatric cases ticked up from 1.13% in the first three months of 2021 to 1 . Per national guidance, this should include persons whose death certificate lists COVID-19 disease or SARS-CoV-2 as an underlying cause of death or as a significant condition contributing to death. Amelia G. Johnson, DrPH1,*; Avnika B. Amin, PhD1,*; Akilah R. Ali, MPH1; Brooke Hoots, PhD1; Betsy L. Cadwell, PhD1; Shivani Arora, MPH2; Tigran Avoundjian, PhD3; Abiola O. Awofeso, DVM4; Jason Barnes, MBA5; Nagla S. Bayoumi, DrPH6; Katherine Busen, MPH7; Carolyn Chang, MPH8; Mike Cima, PhD9; Molly Crockett, MPH10; Alicia Cronquist, MPH11; Sherri Davidson, PhD12; Elizabeth Davis, MA13; Janelle Delgadillo5; Vajeera Dorabawila, PhD14; Cherie Drenzek, DVM15; Leah Eisenstein, MPH16; Hannah E. Fast, MPH17; Ashley Gent, MPH16; Julie Hand, MSPH18; Dina Hoefer, PhD14; Corinne Holtzman, MPH19; Amanda Jara, DVM15; Amanda Jones, MPH20; Ishrat Kamal-Ahmed, PhD21; Sarah Kangas, MPH22; FNU Kanishka, MPH21; Ramandeep Kaur, PhD12; Saadiah Khan, MPH6; Justice King, MSc1; Samantha Kirkendall, MS23; Anna Klioueva, MPH24; Anna Kocharian, MS22; Frances Y. Kwon, MPH2; Jacqueline Logan, MPH25; B. Casey Lyons, MPH26; Shelby Lyons, MPH18; Andrea May, MPH27; Donald McCormick; MSHI9; Erica Mendoza, MAS24; Lauren Milroy, MPH28; Allison ODonnell, MPH10; Melissa Pike, MPH11; Sargis Pogosjans, MPH3; Amy Saupe, MPH19; Jessica Sell, MPH8; Elizabeth Smith, MPH15; Daniel M. Sosin, MD13; Emma Stanislawski, MPH13; Molly K. Steele, PhD1; Meagan Stephenson, MPH1; Allen Stout, MS7; Kyle Strand21; Buddhi P. Tilakaratne, PhD4; Kathryn Turner, PhD23; Hailey Vest, MPH28; Sydni Warner, MS22; Caleb Wiedeman, MPH25; Allison Zaldivar, MPH27; Benjamin J. Before and are much worse at preventing infection or mild disease. Expert groups continue to recommend use of the drug during pregnancy when necessary and in consultation with a doctor. New data from the New Jersey Health Department shows the highly contagious delta variant is causing a higher percentage of breakthrough cases than previously recorded, but the COVID vaccines are still providing extraordinary protection against serious illness and death. Abbreviation: FDA = Food and Drug Administration. Per national guidance, this group should include persons whose death certificate lists COVID-19 disease or SARS-CoV-2 as an underlying cause of death or as a significant condition contributing to death (https://cdn.ymaws.com/www.cste.org/resource/resmgr/pdfs/pdfs2/20211222_interim-guidance.pdf). Between August 12, 2021, and December 6, 2021, 10,236 ED encounters with a primary diagnosis of COVID-19 were observed. Accessed May 15, 2022. * Events per 100,000 population. Those numbers provide only a partial picture of the extent of infections, since they don't include results from at home tests or those who are sick but didn't bother to get tested. The vaccines are not perfect, and the vast majority of vulnerable people have been vaccinated, so the small proportion who get seriously ill still amount to a lot of people. The fall in the share of deaths that are among unvaccinated people could also be explained by changes in the unvaccinated population. Conclusions and relevance: Per national guidance, this should include persons whose death certificate lists COVID-19 disease or SARS-CoV-2 as an underlying cause of death or as a significant condition contributing to death. Data from 41 states are now available. Finally, these data represent 62% of the overall U.S. population, and therefore might not be generalizable. Cases have skyrocketed to historic levels. But while hospitalizations are rising across the country, the states . Variant proportions. Health and Human Services. [A]lthough rooted in the contention that the agency isnt being nearly as straightforward or transparent or comprehensive as they need to be, my tweet could be interpreted as misleading and thats the absolute last thing I want to do so Ive removed it, he wrote. The shots are still good at preventing hospitalization or death, though, particularly if someone has received a booster dose. Why Do Vaccinated People Represent Most COVID-19 Deaths Right Now? Of the 623 breakthrough deaths among vaccinated people in the state, 89% of them were people 65 years old and older. Clipboard, Search History, and several other advanced features are temporarily unavailable. The Henry J. Kaiser Family Foundation Headquarters: 185 Berry St., Suite 2000, San Francisco, CA 94107 | Phone 650-854-9400 Cookies used to make website functionality more relevant to you. Results: Using representative data from 192 509 hospitalizations (see Table 1 for demographic information), monthly COVID-19-associated hospitalization rates ranged from 3.5 times to 17.7 times higher in unvaccinated persons than vaccinated persons regardless of booster dose status. From January to April 2022, when the Omicron variant was . Similarly, to be counted as having a booster, a person must be at least two weeks out from their booster or additional dose before testing positive. Through Monday, 81 per cent of adults 18-plus have received at least one dose, while 73.4 per cent of Ontario's adult population is fully vaccinated. Ascertaining vaccination status for COVID-19 patients through active linkage of case surveillance and immunization information systems typically assumes that cases among persons who are unmatched to the registry are unvaccinated. Standardized definitions were used for COVID-19 cases in fully vaccinated or unvaccinated persons, COVID-19 cases in fully vaccinated persons with booster doses, and COVID-19associated deaths,** with specimen collection dates used as time points. SARS-CoV-2 Vaccination and Clinical Presentation of COVID-19 in Patients Hospitalized during the Delta- and Omicron-Predominant Periods. "If we don't have the medical staff to go out there and take care of patients, it's really going to be all for naught," Callahan said Monday. A previous New York Times story had reported that, when releasing data on COVID-19-associated hospitalizations and deaths among people who are vaccinated and unvaccinated, with or without boosters . Excluded were partially vaccinated persons who had received at least one FDA-authorized or approved vaccine dose but did not complete a primary series 14 days before collection of a specimen with SARS-CoV-2 RNA or antigen detected. The number of observations informing each CI reflects the number of weeks per period: OctoberNovember (7), and December (4). Despite more breakthrough cases, unvaccinated patients still make up the majority of COVID hospitalizations, according to data from the New Jersey Hospital Association. Against omicron, however, the vaccines havent. According to the CDC website, COVID-19 case and death information is collected from jurisdictions that can link their case surveillance data to immunization data, and identify the vaccination status of people who test positive. Relative vaccine effectiveness of a SARS-CoV-2 mRNA vaccine booster dose against the Omicron variant. See this image and copyright information in PMC. Unvaccinated people face a 20 times greater risk of dying from Covid-19 and a 10 times greater risk of testing positive than fully-vaccinated people who have also received a booster, according to . This change requires a reload. SARS-CoV-2 B.1.1.529 (Omicron) variantUnited States, December 18, 2021. Rates of COVID-19 Cases or Deaths by Age Group and Vaccination Status Public Use Data (version date: February 22, 2023). Importance: 31 Mar 2022. But by January 2022, as we showed in an analysis posted on the Peterson-KFF Health System Tracker, about 4 in 10 deaths were vaccinated or boosted. Concern about omicron among the unvaccinated dropped from 52% to 44% between December 24 and 30, the Morning Consult poll found, which was conducted among 2,220 U.S. adults. All information these cookies collect is aggregated and therefore anonymous. There are many more vaccinated people than there are unvaccinated people, and vaccinated and boosted people are, on average, older and more likely to have underlying health conditions that put them at risk for severe COVID-19 outcomes. Comparative admission rates and infection severity of COVID-19 among unvaccinated and vaccinated patients. DOI: http://dx.doi.org/10.15585/mmwr.mm7104e2. More transmission can also lead to more deaths. Ongoing analyses will help monitor the impact of the Omicron variant and other emerging variants on VE against COVID-19 cases and associated deaths; rates by vaccination status will be updated monthly on CDCs COVID Data Tracker website (3). Hospitalizations have doubled or nearly doubled in Connecticut, Delaware, New Hampshire, New Jersey and New York since Nov. 1. You can also edit metadata from this page. Drs Reeg and Kohrman reported grants from the Michigan Department of Health and Human Services during the conduct of the study. A COVID-19 case in an unvaccinated person occurred when the person did not receive any FDAauthorized COVID-19 vaccine doses before the specimen collection date. Silk, PhD1; Heather M. Scobie, PhD1 (View author affiliations). meets with refugee families. Similarly, as the share of the population with a booster rose somewhat during 2022, the share of deaths among boosted people also rose. However, the rising share of the population that is vaccinated is only part of the story and does not seem to explain all of the rise in the share of deaths that are among vaccinated people over the last year. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Characteristics of the two groups can be viewed in Table 1. Of the 378 new COVID-positive hospitalizations statewide for those dates, 97%, or 367 of 378, were people who were either unvaccinated or not yet fully vaccinated, he said. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Johnson AG, Amin AB, Ali AR, Hoots B, Cadwell BL, Arora S, Avoundjian T, Awofeso AO, Barnes J, Bayoumi NS, Busen K, Chang C, Cima M, Crockett M, Cronquist A, Davidson S, Davis E, Delgadillo J, Dorabawila V, Drenzek C, Eisenstein L, Fast HE, Gent A, Hand J, Hoefer D, Holtzman C, Jara A, Jones A, Kamal-Ahmed I, Kangas S, Kanishka F, Kaur R, Khan S, King J, Kirkendall S, Klioueva A, Kocharian A, Kwon FY, Logan J, Lyons BC, Lyons S, May A, McCormick D; MSHI; Mendoza E, Milroy L, O'Donnell A, Pike M, Pogosjans S, Saupe A, Sell J, Smith E, Sosin DM, Stanislawski E, Steele MK, Stephenson M, Stout A, Strand K, Tilakaratne BP, Turner K, Vest H, Warner S, Wiedeman C, Zaldivar A, Silk BJ, Scobie HM. In particular, the story said the CDC left out data on the effectiveness of boosters in people ages 18 to 49. On November 19, 2021, and November 29, 2021, CDC expanded recommendations for booster doses to include all adults aged 18 years (https://www.cdc.gov/media/releases/2021/s1119-booster-shots.html, https://www.cdc.gov/media/releases/2021/s1129-booster-recommendations.html). COVID hospitalization in NJ reach 8-month high. Centers for Disease Control and Prevention, COVID-19 Response. Accessibility MMWR Morb Mortal Wkly Rep. 2022 Jan 28;71(4):125-131. doi: 10.15585/mmwr.mm7104e1. Since the vaccine rollout began last December, less than one third of 1% of fully vaccinated Garden State residents have tested positive for COVID, and of the more than 5 million people fully vaccinated by the end of August, a total of 386 have been hospitalized. Murphy, Murphy: No link between wind power and NJ whale deaths, Surprise visit to Ukraine NJ Gov. With more than a dozen dead whales, Gov. And all 80 COVID deaths recorded that week were people who had not been vaccinated. The next update for rates of cases and deaths by vaccination status will be mid-April and include case data through mid-March and death data through late February. However, this protection from a past infection can also diminish over time, which is why it is still recommended that unvaccinated people with prior COVID-19 infections get vaccinated and stay up-to-date on boosters. Reed, Jasmine. State immunization information system data were linked to cases, and the vaccination coverage data of the defined catchment population were used to compare hospitalization rates in unvaccinated and vaccinated individuals. That's a rate of 1.8% a higher rate compared to the data we have on breakthrough infections. First, booster doses could not be distinguished from additional primary doses administered to immunocompromised persons, which could result in reduced IRRs because of lower VE in this population. In 25 U.S. jurisdictions, decreases in case incidence rate ratios for unvaccinated versus fully vaccinated persons with and without booster vaccine doses were observed when the Omicron variant emerged in December 2021. 2023 Jan 26;12(3):961. doi: 10.3390/jcm12030961. If the Janssen vaccine was either the first dose or the second dose, the series type was called Janssen. Accorsi EK, Britton A, Fleming-Dutra KE, et al. *** https://www.cdc.gov/nchs/data/statnt/statnt24.pdf. TheNovavax vaccine, which was authorized in July 2022, had a 90.4% efficacy in preventing symptomatic COVID-19 in adults, prior to the emergence of the omicron variant. FOIA When looking at deaths, the difference between being vaccinated and unvaccinated was much more drastic. The C.D.C. On October 21, 2021, CDC recommended a booster dose for adults aged 18 years who received the Janssen vaccine and for Pfizer-BioNTech or Moderna primary series recipients, including all adults aged 65 years and persons aged 18 years in certain populations and high risk occupational and institutional settings. Laboratory-confirmed COVID-19-associated hospitalization, defined as a positive SARS-CoV-2 test result within 14 days before or during hospitalization. Weekly / January 28, 2022 / 71(4);132138. During that same time . A COVID-19 case in a fully vaccinated person with a booster dose occurred when a person had SARS-CoV-2 RNA or antigen detected on a respiratory specimen collected 14 days after receipt of at least one additional or booster dose of any COVID-19 vaccine on or after August 13, 2021. Drs Billing and Shiltz reported grants from the Council of State and Territorial Epidemiologists (CTSTE) and the CDC Dr Schaffner reported grants from CDC during the conduct of the study as well as personal fees from VBI Vaccines outside the submitted work. Kheriaty was making reference to a New York Times story published on Feb. 20 that reported the CDC had withheld critical data on boosters, hospitalizations and wastewater analyses. You can review and change the way we collect information below. , and New data this week has found fully vaccinated adults 65 or older are 94% less . ; Surveillance Platform for Enteric and Respiratory Infectious Organisms at the VA COVID-19 Surveillance Group . Sect. Thats why, when CDC adjusts for some of these factors (age and population size), we still see that unvaccinated people are at much greater risk of death and other severe outcomes than people the same age who have stayed up-to-date on boosters. . These time frames allow the subject matter experts to process and complete a thorough analysis of the data, CDC spokeswoman Jasmine Reed told us in an email. The state is asking FEMA to send strike forces to bolster hospital staff and National Guard to help depleted nursing home staff as COVID spikes. Please choose whether or not you wish to save this view before you leave; or choose Cancel to return to the page. Those who had received a booster vaccine dose as well had a 94% lower risk. Vaccinations for COVID-19 began being administered in the U.S. on Dec. 14, 2020. Beds occupied by non-Covid-19 patients (ICU and Inpatient), which appear in teal. What are the implications for public health practice? Rates of COVID-19 Cases and Deaths by Vaccination Status. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. The age-standardized IRR for cases in unvaccinated versus fully vaccinated persons was 13.9 during AprilMay and progressively declined to 8.7 during June, 5.1 during JulyNovember, and 3.1 during December, coinciding with the periods of Delta emergence, Delta predominance, and Omicron emergence, respectively. , a surveillance system that collects data on hospitalizations of children and adults with a confirmed infection through a network of over 250 hospitals in 14 states. A COVID-19 case in a fully vaccinated person with a booster dose occurred when a person had SARS-CoV-2 RNA or antigen detected on a respiratory specimen collected 14 days after receipt of at least one additional or booster dose of any COVID-19 vaccine on or after August 13, 2021. When accounting for total population and differences in the risk of severe disease among all ages, the rate of COVID-19-related hospitalization among those with at least two vaccine doses is 124.9 . Use of wastewater metrics to track COVID-19 in the U.S.: a national time-series analysis over the first three quarters of 2022. President Joe Biden visited Somerset County on Tuesday, Sept. 7, 2021, for a meeting with state and county officials in Hillsborough and a tour of storm damage in Manville. A COVID-19 case in an unvaccinated person occurred when the person did not receive any FDA-authorized COVID-19 vaccine doses before the specimen collection date. This finding actually underscores the importance of staying up-to-date on boosters.